The aim of the study was the estimation of substernal goiter by use of three-dimensional spiral computed tomography (3-D sCT) with the contrast agent. The size and anatomy of goiter as well as its relation to surrounding tissues, particularly blood vessels was evaluated. The examination allowed good visualization of both inferior thyroid arteries. The use of 3-D sCT may have a great meaning in preoperative examination in particular in technically difficult cases of substernal goiter.