Abstract
Neurons and brain macrophages (BM), respectively, increase and inhibit gap junctional communication (GJC) and connexin expression in cultured astrocytes. Thus, in brain diseases and injuries, neuronal death associated with the BM activation may decrease GJC in astrocytes and therefore have a physiopathological relevance.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Animals
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Astrocytes / cytology
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Astrocytes / metabolism*
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Brain / cytology
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Brain / metabolism*
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Cell Communication / physiology
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Connexins / metabolism*
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Gap Junctions / metabolism
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Macrophages / cytology
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Macrophages / metabolism*
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Neurons / cytology
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Neurons / metabolism*