Successful treatment of musk ketone-induced chronic actinic dermatitis with cyclosporine and PUVA

J Am Acad Dermatol. 1992 Nov;27(5 Pt 2):838-42. doi: 10.1016/0190-9622(92)70261-d.

Abstract

We describe a patient with chronic actinic dermatitis whose photopatch tests revealed reactions to musk ketone and musk ambrette, both of which were found in his aftershave lotion. Minimal erythema doses of UVA and UVB were decreased. After initial unsuccessful treatment with PUVA therapy the patient was successfully treated with a combination of cyclosporine and PUVA.

Publication types

  • Case Reports

MeSH terms

  • Chronic Disease
  • Cyclosporine / administration & dosage
  • Cyclosporine / therapeutic use*
  • Dinitrobenzenes / adverse effects*
  • Drug Therapy, Combination
  • Humans
  • Ketones / adverse effects*
  • Male
  • Middle Aged
  • PUVA Therapy*
  • Perfume / adverse effects*
  • Photosensitivity Disorders / drug therapy*
  • Photosensitivity Disorders / etiology
  • Photosensitivity Disorders / pathology

Substances

  • Dinitrobenzenes
  • Ketones
  • Perfume
  • musk ambrette (artificial)
  • Cyclosporine