Antigen-specific T cells: analyses of the needles in the haystack

PLoS Biol. 2003 Dec;1(3):E78. doi: 10.1371/journal.pbio.0000078. Epub 2003 Dec 22.

Abstract

Antigen binding to T cell receptors is a critical step in an immune response. Detection and characterization of rare populations of T cells enhances our ability to understand and treat disease

Publication types

  • Review

MeSH terms

  • Histocompatibility Antigens Class I / chemistry*
  • Histocompatibility Antigens Class II / chemistry*
  • Humans
  • Ligands
  • Lymphocyte Activation
  • Major Histocompatibility Complex*
  • Models, Molecular
  • Protein Conformation
  • Receptors, Antigen, T-Cell / chemistry*
  • T-Lymphocytes / chemistry
  • T-Lymphocytes / cytology*

Substances

  • Histocompatibility Antigens Class I
  • Histocompatibility Antigens Class II
  • Ligands
  • Receptors, Antigen, T-Cell