Methemoglobinemia and hemolysis after enteral administration of methylene blue in a preterm infant: relevance for pediatric surgeons

J Pediatr Surg. 2004 Jan;39(1):E35-7. doi: 10.1016/j.jpedsurg.2003.09.045.

Abstract

A preterm infant had methaemoglobulinemia and hemolytic anemia after enteral administration of methylene blue. The dye was administered to exclude a tracheoesophageal fistula. Methylene blue is a noxious product, especially in neonates. It should be considered a potential cause of acquired methemoglobulinemia, even after enteral administration.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Esophagus
  • Female
  • Hemolysis*
  • Humans
  • Infant, Newborn
  • Infant, Premature
  • Infant, Premature, Diseases / chemically induced*
  • Infant, Premature, Diseases / diagnosis
  • Intubation
  • Methemoglobinemia / chemically induced*
  • Methemoglobinemia / diagnosis
  • Methylene Blue / administration & dosage
  • Methylene Blue / adverse effects*
  • Tracheoesophageal Fistula / diagnosis

Substances

  • Methylene Blue