Syntheses and radical scavenging activities of resveratrol derivatives

Hyun Jung Lee; Jai Woong Seo; Bong Ho Lee; Kyoo Hyun Chung; Dae Yoon Chi

doi:10.1016/j.bmcl.2003.10.038

Syntheses and radical scavenging activities of resveratrol derivatives

Bioorg Med Chem Lett. 2004 Jan 19;14(2):463-6. doi: 10.1016/j.bmcl.2003.10.038.

Authors

Hyun Jung Lee¹, Jai Woong Seo, Bong Ho Lee, Kyoo Hyun Chung, Dae Yoon Chi

Affiliation

¹ Department of Chemistry, Inha University, 253 Yonghyundong, Namgu, 402-751, Inchon, South Korea.

PMID: 14698182
DOI: 10.1016/j.bmcl.2003.10.038

Abstract

Nine new resveratrol derivatives, having bromo, iodo, and fluoroethyl groups, were designed and synthesized. All compounds having free phenol groups showed good free radical scavenging activity. Among them, 2-bromoresveratrol 19 has a similar free radical scavenging activity to (+)-catechin.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Antioxidants / chemical synthesis
Antioxidants / metabolism
Free Radical Scavengers / chemical synthesis*
Free Radical Scavengers / metabolism
Resveratrol
Stilbenes / chemical synthesis*
Stilbenes / metabolism

Substances

Antioxidants
Free Radical Scavengers
Stilbenes
Resveratrol