Abstract
A new triterpenoid, 2alpha,3alpha,24-trihydroxyurs-12-en-28-oic acid-28-O-beta-D-glucopyranosyl ester (4) along with four known triterpenoids, ursolic acid (1), 2alpha-hydroxyursolic acid (2), 2alpha,3alpha,24-trihydroxyurs-12-en-28-oic acid (3), and 2alpha,3alpha,19alpha,24-tetrahydroxyurs-12-en-28-oic acid-28-O-beta-D-glucopyranosyl ester (5), were isolated from the leaves of Prunus serrulata var. spontanea (Rosaceae). Compounds 3-5 showed ONOO(-) scavenging activity, whereas compounds 1 and 2 were virtually inactive.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Free Radical Scavengers / chemistry
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Free Radical Scavengers / isolation & purification
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Glycosides / chemistry
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Glycosides / isolation & purification
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Magnetic Resonance Spectroscopy
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Monosaccharides / chemistry*
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Monosaccharides / isolation & purification
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Penicillamine / chemistry
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Peroxynitrous Acid / chemistry
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Plant Leaves / chemistry
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Prunus / chemistry*
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Spectrometry, Mass, Fast Atom Bombardment
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Spectrophotometry, Infrared
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Spectroscopy, Fourier Transform Infrared
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Triterpenes / chemistry*
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Triterpenes / isolation & purification
Substances
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2alpha,3alpha,24-trihydroxyurs-12-en-28-oic acid-28-O-beta-D-glucopyranosyl ester
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Free Radical Scavengers
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Glycosides
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Monosaccharides
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Triterpenes
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Peroxynitrous Acid
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Penicillamine