Primary cutaneous CD30-positive lymphoproliferative disorders

Hematol Oncol Clin North Am. 2003 Dec;17(6):1319-32, vii-viii. doi: 10.1016/s0889-8588(03)00117-5.

Abstract

Primary cutaneous CD30-positive (anaplastic) large T-cell lymphoma and lymphomatoid papulosis have many overlapping clinical, histologic, and immunophenotypic features. These entities are currently considered as parts of a spectrum of primary cutaneous CD30-positive lymphoproliferative disorders. We provide the clinician with practical guidelines for the diagnosis, management, and treatment of patients within this spectrum of primary cutaneous CD30-positive lymphoproliferative disorders. Most patients within this spectrum of disease have an excellent prognosis. Multi-agent chemotherapy should be reserved for patients who have extracutaneous disease.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Cell Transformation, Neoplastic
  • Child
  • Child, Preschool
  • Diagnosis, Differential
  • Female
  • Humans
  • Infant
  • Lymphoma, Large-Cell, Anaplastic* / diagnosis
  • Lymphoma, Large-Cell, Anaplastic* / epidemiology
  • Lymphoma, Large-Cell, Anaplastic* / etiology
  • Lymphoma, Large-Cell, Anaplastic* / pathology
  • Lymphoma, Large-Cell, Anaplastic* / therapy
  • Lymphomatoid Papulosis / etiology
  • Lymphomatoid Papulosis / pathology
  • Male
  • Middle Aged
  • Remission, Spontaneous
  • Skin Neoplasms* / diagnosis
  • Skin Neoplasms* / epidemiology
  • Skin Neoplasms* / etiology
  • Skin Neoplasms* / pathology
  • Skin Neoplasms* / therapy
  • Virus Diseases / complications