Vitamin D intoxication and hypercalcaemia in an infant treated with pamidronate infusions

Eur J Pediatr. 2004 Mar;163(3):163-5. doi: 10.1007/s00431-003-1387-4. Epub 2004 Jan 9.

Abstract

Bisphosphonates are used for the treatment of childhood hypercalcaemia, especially that due to malignancies. Here we report the use of intravenous pamidronate for the treatment of hypercalcaemia due to vitamin D intoxication in a 3-month-old infant. Serum calcium levels were normalised without complications.

Conclusion: pamidronate may be used in hypercalcaemia due to vitamin D intoxication in paediatric cases resistant to hydration, diuretics or corticosteroids.

Publication types

  • Case Reports

MeSH terms

  • Anti-Inflammatory Agents / therapeutic use*
  • Diphosphonates / therapeutic use*
  • Humans
  • Hypercalcemia / drug therapy*
  • Hypercalcemia / etiology
  • Infant
  • Infusions, Intravenous
  • Male
  • Pamidronate
  • Rickets / drug therapy*
  • Vitamin D / poisoning*

Substances

  • Anti-Inflammatory Agents
  • Diphosphonates
  • Vitamin D
  • Pamidronate