This article introduces the mechanisms and theories behind the surgical treatments for heart failure; however, heart failure is a complex problem and requires multiple solutions. Surgery offers treatment strategies that target underlying physiologic changes and may provide both quality of life and survival benefit to patients who have specific clinical characteristics consistent with the aims of the procedure. Nurses must include surgical treatment early in their hierarchy of treatment plans, especially when coronary artery occlusion, hibernating myocardium, or mitral valve regurgitation is the cause of heart failure. In addition, newer investigational surgical therapies must also be considered for patients with advanced heart failure who have already been optimized on medical and cardiac resynchronization therapies and who require a novel approach to potentially improve individual outcomes.