Hypercalcemia induced by parathyroid hormone-related peptide after treatment of squamous cell carcinoma of oral cavity

J Assoc Physicians India. 2003 Oct:51:1023-4.

Abstract

Squamous cell carcinoma of the head and neck is a rare cause of humoral hypercalcemia of malignancy. This paraneoplastic syndrome is usually one of the presenting symptoms of the disease. We report a case of squamous cell carcinoma of the oral cavity that presumably elaborated parathyroid hormone-related peptide (PTH-rP) and caused hypercalcemia only after radiotherapy and chemotherapy.

Publication types

  • Case Reports

MeSH terms

  • Carcinoma, Squamous Cell / metabolism
  • Carcinoma, Squamous Cell / therapy*
  • Hormones, Ectopic / metabolism
  • Humans
  • Hypercalcemia / etiology*
  • Hypercalcemia / therapy
  • Male
  • Middle Aged
  • Mouth Neoplasms / metabolism
  • Mouth Neoplasms / therapy*
  • Paraneoplastic Syndromes* / therapy
  • Parathyroid Hormone-Related Protein / metabolism

Substances

  • Hormones, Ectopic
  • Parathyroid Hormone-Related Protein