Psychological implications of situations that may take place during a mission to Mars including desynchronosis, fatigue, psychic asthenization, acute mental disorders, interruption of the information flow, unpredicted transformation of the socio-psychological needs, a persistent conflict tension in the crew, errors in manual control of the vehicle, refusal or impossibility to fulfill an operation, difficulties in communication between the crew and ground controllers were analyzed for determination of their causes and consequences, probable starting time, ways and methods of preventing and surmounting each of these situations.