GAPSCORE: finding gene and protein names one word at a time

Bioinformatics. 2004 Jan 22;20(2):216-25. doi: 10.1093/bioinformatics/btg393.

Abstract

Motivation: New high-throughput technologies have accelerated the accumulation of knowledge about genes and proteins. However, much knowledge is still stored as written natural language text. Therefore, we have developed a new method, GAPSCORE, to identify gene and protein names in text. GAPSCORE scores words based on a statistical model of gene names that quantifies their appearance, morphology and context.

Results: We evaluated GAPSCORE against the Yapex data set and achieved an F-score of 82.5% (83.3% recall, 81.5% precision) for partial matches and 57.6% (58.5% recall, 56.7% precision) for exact matches. Since the method is statistical, users can choose score cutoffs that adjust the performance according to their needs.

Availability: GAPSCORE is available at http://bionlp.stanford.edu/gapscore/

Publication types

  • Comparative Study
  • Evaluation Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.
  • Validation Study

MeSH terms

  • Abstracting and Indexing
  • Algorithms*
  • Artificial Intelligence
  • Database Management Systems
  • Dictionaries as Topic
  • Genes*
  • Information Storage and Retrieval / methods*
  • Natural Language Processing*
  • Pattern Recognition, Automated*
  • Periodicals as Topic*
  • Proteins*
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Software
  • Terminology as Topic*

Substances

  • Proteins