Abstract
Agrobacteria are a group of phytopathogenic organisms widely distributed in soil; they are now recognized as rare human pathogens affecting mostly immunocompromised hosts. We report a case of catheter-related bacteremia due to Agrobacterium radiobacter in a neutropenic patient and describe the clinical presentations, treatment strategies and outcome of Agrobacterium infections based on our experience and a literature review. The antimicrobial susceptibility patterns of these organisms appear to be quite variable and collective susceptibility data derived from this and previous reports are provided.
MeSH terms
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Agrobacterium tumefaciens / isolation & purification*
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Anti-Bacterial Agents
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Antineoplastic Combined Chemotherapy Protocols / administration & dosage
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Antineoplastic Combined Chemotherapy Protocols / adverse effects
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Bacteremia / diagnosis*
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Bacteremia / drug therapy
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Bacteremia / etiology
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Bone Neoplasms / drug therapy
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Bone Neoplasms / pathology
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Bone Neoplasms / surgery
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Catheters, Indwelling / adverse effects*
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Catheters, Indwelling / microbiology
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Drug Therapy, Combination / administration & dosage
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Follow-Up Studies
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Gram-Negative Bacterial Infections / drug therapy
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Gram-Negative Bacterial Infections / microbiology*
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Humans
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Lung Neoplasms / drug therapy
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Lung Neoplasms / secondary
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Male
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Middle Aged
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Osteosarcoma / drug therapy
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Osteosarcoma / secondary
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Osteosarcoma / surgery
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Risk Assessment
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Severity of Illness Index
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Treatment Outcome