Synthesis of 2-N,N-dimethylaminomethyl-2,3,3a,12b-tetrahydrodibenzo-[b,f]furo[2,3-d]oxepin derivatives as potential anxiolytic agents

Chem Pharm Bull (Tokyo). 2004 Feb;52(2):262-5. doi: 10.1248/cpb.52.262.

Abstract

New synthesis approaches that have led to a series of novel tetrahydrodibenzo[b,f]furo[2,3-d]oxepin derivatives are described. According to preliminary data these novel tetracycles can be useful intermediates for the preparation of potential new therapeutic agents.

MeSH terms

  • Anti-Anxiety Agents / chemical synthesis*
  • Anti-Anxiety Agents / chemistry
  • Cyclization
  • Indicators and Reagents
  • Magnetic Resonance Spectroscopy
  • Molecular Structure
  • Oxepins / chemical synthesis*
  • Oxepins / chemistry
  • Stereoisomerism

Substances

  • Anti-Anxiety Agents
  • Indicators and Reagents
  • Oxepins