Abstract
The Salmonella effector protein SopA is translocated into host cells via the SPI-1 type III secretion system (TTSS) and contributes to enteric disease. We found that the chaperone InvB binds to SopA and slightly stabilizes it in the bacterial cytosol and that it is required for its transport via the SPI-1 TTSS.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Bacterial Proteins / genetics
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Bacterial Proteins / metabolism*
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Bacterial Proteins / physiology*
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Cytosol / metabolism
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Protein Transport
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Salmonella typhimurium / metabolism*
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Transcription, Genetic
Substances
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Bacterial Proteins
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invB protein, Salmonella
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SopA protein, Bacteria