Spinal cord compression in beta-thalassemia: case report and review of the literature

Spinal Cord. 2004 Feb;42(2):117-23. doi: 10.1038/sj.sc.3101544.

Abstract

Study design: A case report of thoracic spinal cord compression in a 34-year-old male with beta-thalassemia is reported.

Objectives: In patients with thalassemia, neurologic complaints should lead to a high index of suspicion for spinal cord compression from marrow expansion, ectopic bone formation and resultant stenosis. Initial presentation, diagnosis, radiographic findings, surgical treatment and follow-up are reviewed.

Setting: This case is reported from Chicago, Illinois.

Method: A chart review is performed for the purposes of this case report.

Results: Patient underwent decompressive laminectomy with good surgical outcome.

Conclusion: Rapid diagnosis and treatment of such a condition is essential to optimize the chances of recovery.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Bone Marrow / pathology
  • Bone Marrow / physiopathology
  • Choristoma / complications*
  • Choristoma / diagnosis
  • Choristoma / diagnostic imaging
  • Dexamethasone / therapeutic use
  • Hematopoiesis, Extramedullary / physiology*
  • Humans
  • Laminectomy
  • Magnetic Resonance Imaging
  • Male
  • Recovery of Function / physiology
  • Regional Blood Flow / physiology
  • Spinal Canal / diagnostic imaging
  • Spinal Canal / pathology
  • Spinal Cord / diagnostic imaging
  • Spinal Cord / pathology*
  • Spinal Cord / physiopathology
  • Spinal Cord Compression / diagnosis*
  • Spinal Cord Compression / diagnostic imaging
  • Spinal Cord Compression / etiology*
  • Thoracic Vertebrae / pathology*
  • Thoracic Vertebrae / physiopathology
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • beta-Thalassemia / complications*

Substances

  • Dexamethasone