Upper gastrointestinal endoscopic findings in patients with HIV/AIDS at the Jos University Teaching Hospital, Nigeria

Niger J Med. 2003 Oct-Dec;12(4):202-5.

Abstract

Background: Upper gastrointestinal tract involvement in HIV/AIDS is common. No data exist on the pattern of upper gastrointestinal endoscopic findings in HIV/AIDS patients in Nigeria.

Objective: To describe the pattern of upper gastrointestinal endoscopic findings in HIV/AIDS patients.

Design: A hospital based retrospective case-control study involving 52 HIV/AIDS patients and 52 age and sex matched controls.

Setting: Medicine Department of the Jos University Teaching Hospital, Nigeria.

Methods: Medical records of patients with HIV/AIDS and an age and gender matched control who underwent upper gastrointestinal endoscopy over an eight-year period were reviewed.

Results: Oesophageal candidiasis was the commonest finding in 18 (34.6%) of subjects with HIV/AIDS followed by normal upper gastrointestinal tract in 17 (32.1%). Normal upper gastrointestinal tract was found in 57.6% of HIV seronegative subjects while oesophageal candidiasis occurred in one (1.9%) of these patients. Duodenal ulcer and gastritis occurred with equal frequencies in HIV/AIDS patients (7.5%) and controls.

Conclusion: Oesophageal candidiasis was the commonest upper gastrointestinal endoscopic finding in patients with HIV/AIDS.

MeSH terms

  • AIDS-Related Opportunistic Infections / epidemiology
  • Adult
  • Age Distribution
  • Aged
  • Candidiasis / epidemiology
  • Case-Control Studies
  • Comorbidity
  • Endoscopy / statistics & numerical data
  • Female
  • Gastrointestinal Diseases / diagnosis
  • Gastrointestinal Diseases / epidemiology*
  • HIV Infections / epidemiology*
  • Hospitals, Teaching / statistics & numerical data
  • Humans
  • Male
  • Middle Aged
  • Nigeria / epidemiology
  • Retrospective Studies
  • Sex Distribution