Role for botulinum toxin in back pain treatment in adults with cerebral palsy: report of a case

Joint Bone Spine. 2004 Jan;71(1):76-8. doi: 10.1016/S1297-319X(03)00124-6.

Abstract

Objective: To report a case illustrating the usefulness of botulinum toxin A in the treatment of spinal dystonia responsible for low back pain and postural disorders.

Methods: Critical appraisal of a case report.

Case report: A young woman with cerebral palsy had lumbar paraspinal muscle dystonia responsible for pain and hyperlordosis unresponsive to oral medications for muscle spasm. Botulinum toxin A (Botox(R), 200 U) was injected into the paraspinal muscles at six sites, to good effect.

Discussion: The few reported cases consistently show a favorable effect of local botulinum toxin A injections in patients with painful paraspinal muscle dystonia related to neurological disease or chronic low back pain.

Conclusion: Botulinum toxin A may be a useful treatment for incapacitating painful dystonia of the paraspinal muscles. This treatment improves posture in the sitting position and facilitates the fitting of orthotic devices. Furthermore, botulinum toxin A treatment may help to determine whether an intrathecal baclofen test is in order.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Botulinum Toxins, Type A / administration & dosage
  • Botulinum Toxins, Type A / therapeutic use*
  • Cerebral Palsy / complications
  • Cerebral Palsy / physiopathology*
  • Dystonia / complications
  • Dystonia / physiopathology*
  • Female
  • Humans
  • Injections, Intramuscular
  • Low Back Pain / drug therapy*
  • Low Back Pain / etiology
  • Neuromuscular Agents / administration & dosage
  • Neuromuscular Agents / therapeutic use*

Substances

  • Neuromuscular Agents
  • Botulinum Toxins, Type A