Increased right caudate nucleus size in obsessive-compulsive disorder: detection with magnetic resonance imaging

S Scarone; C Colombo; S Livian; M Abbruzzese; P Ronchi; M Locatelli; G Scotti; E Smeraldi

doi:10.1016/0925-4927(92)90005-o

Increased right caudate nucleus size in obsessive-compulsive disorder: detection with magnetic resonance imaging

Psychiatry Res. 1992 Aug;45(2):115-21. doi: 10.1016/0925-4927(92)90005-o.

Authors

S Scarone¹, C Colombo, S Livian, M Abbruzzese, P Ronchi, M Locatelli, G Scotti, E Smeraldi

Affiliation

¹ Department of Biomedical and Technological Sciences, University of Milan Medical School, Italy.

PMID: 1488469
DOI: 10.1016/0925-4927(92)90005-o

Abstract

Magnetic resonance images were used to measure the volume of the head of the caudate nucleus in 20 patients with obsessive-compulsive disorder and 16 normal control subjects. The obsessive-compulsive patients showed a significant increase in the volume of the right side of the head of the caudate nucleus compared with that of control subjects. This finding was not correlated with demographic, psychopathological, or clinical characteristics.

Publication types

Comparative Study

MeSH terms

Adult
Basal Ganglia
Brain / diagnostic imaging
Brain / drug effects
Clomipramine / administration & dosage
Clomipramine / therapeutic use
Female
Fluvoxamine / administration & dosage
Fluvoxamine / therapeutic use
Functional Laterality
Humans
Magnetic Resonance Imaging*
Male
Obsessive-Compulsive Disorder / classification
Obsessive-Compulsive Disorder / diagnosis*
Obsessive-Compulsive Disorder / drug therapy
Psychiatric Status Rating Scales
Radiography
Trigeminal Caudal Nucleus / abnormalities*
Trigeminal Caudal Nucleus / diagnostic imaging
Trigeminal Caudal Nucleus / drug effects

Substances

Clomipramine
Fluvoxamine