Abstract
Exposure of human neutrophils to a conventional, acidic, lactate-containing peritoneal dialysis solution (PDS) resulted in the development of a prompt and substantial intracellular acidosis. It is possible that this intracellular acidosis contributes to cellular dysfunction.
MeSH terms
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Adult
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Centrifugation, Density Gradient
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Dialysis Solutions / adverse effects*
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Female
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Humans
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Hydrogen-Ion Concentration
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Lactates / adverse effects*
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Lactic Acid
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Male
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Neutrophils / drug effects*
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Neutrophils / metabolism
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Peritoneal Dialysis*
Substances
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Dialysis Solutions
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Lactates
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Lactic Acid