[Advanced carcinoma of the prostate (stages C and D). Mortality within 12 months of the initiation of hormonal therapy]

Minerva Urol Nefrol. 1992 Jul-Sep;44(3):205-8.
[Article in Italian]

Abstract

Seventy-three patients with stage C and D prostatic carcinoma were treated with hormonotherapy. During a mean follow-up of 27 +/- 17.8 months, 30 tumour-related deaths were registered. The patients in the G3 subset suffered a 35.7% early death rate versus a 10.1% rate of G1-2 ones. This difference is significant (p = 0.0102). Nevertheless the Authors' opinion is that G3 patients should not be given a more aggressive treatment initially apart from the case of a controlled trial.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Aged
  • Aged, 80 and over
  • Carcinoma / drug therapy
  • Carcinoma / mortality*
  • Carcinoma / pathology
  • Carcinoma / surgery
  • Combined Modality Therapy
  • Flutamide / therapeutic use*
  • Goserelin / therapeutic use*
  • Humans
  • Life Tables
  • Male
  • Middle Aged
  • Neoplasm Staging
  • Orchiectomy
  • Prostatic Neoplasms / drug therapy
  • Prostatic Neoplasms / mortality*
  • Prostatic Neoplasms / pathology
  • Prostatic Neoplasms / surgery
  • Survival Analysis
  • Survival Rate

Substances

  • Goserelin
  • Flutamide