Special details of animal haemostaseological investigations are insufficiently known as yet. This concerns as well the use of standardized laboratory methods as the differences between species and the normal ranges. Global tests and determinations of activity of single blood clotting factors (II, V, VII - XII, AT III) were carried out on healthy pigs and cattle. Quantitative evaluations were performed by using human or animal reference plasmas. Special attention was paid to the determinations of single blood clotting factors.