Linkage analysis of systolic blood pressure: a score statistic and computer implementation

BMC Genet. 2003 Dec 31;4 Suppl 1(Suppl 1):S77. doi: 10.1186/1471-2156-4-S1-S77.

Abstract

A genome-wide linkage analysis was conducted on systolic blood pressure using a score statistic. The randomly selected Replicate 34 of the simulated data was used. The score statistic was applied to the sibships derived from the general pedigrees. An add-on R program to GENEHUNTER was developed for this analysis and is freely available.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Age Factors
  • Blood Pressure / genetics*
  • Chromosome Mapping / statistics & numerical data
  • Chromosomes, Human, Pair 16 / genetics
  • Chromosomes, Human, Pair 4 / genetics
  • Cohort Studies
  • Computer Simulation / statistics & numerical data*
  • Female
  • Genetic Linkage / genetics*
  • Genetic Testing / statistics & numerical data
  • Genome, Human
  • Humans
  • Male
  • Quantitative Trait Loci / genetics
  • Software / statistics & numerical data