Postnatal steroid treatment and brain development

Arch Dis Child Fetal Neonatal Ed. 2004 Mar;89(2):F96-100. doi: 10.1136/adc.2003.028696.

Abstract

This review examines the risk/benefit ratio of postnatal steroid treatment in preterm infants and correlates epidemiological data with experimental evidence on the effect of glucocorticosteroids on brain development.

Publication types

  • Review

MeSH terms

  • Animals
  • Brain / anatomy & histology
  • Brain / growth & development*
  • Cerebral Palsy / pathology
  • Cerebral Palsy / prevention & control*
  • Child Development / drug effects*
  • Dexamethasone / adverse effects*
  • Dexamethasone / therapeutic use
  • Glucocorticoids / adverse effects*
  • Glucocorticoids / therapeutic use
  • Humans
  • Infant, Newborn
  • Infant, Premature
  • Leukomalacia, Periventricular / prevention & control*
  • Magnetic Resonance Imaging
  • Risk Assessment

Substances

  • Glucocorticoids
  • Dexamethasone