[Progress in researches on sperm antigen fertilin beta]

Jun Zhang; Yanfeng Li

[Progress in researches on sperm antigen fertilin beta]

Zhonghua Nan Ke Xue. 2004 Jan;10(1):52-4, 58.

[Article in Chinese]

Authors

Jun Zhang¹, Yanfeng Li

Affiliation

¹ Department of Urology, Institute of Surgery, Daping Hospital, Third Military Medical University, Chongqing, 400042, China.

PMID: 14979211

Abstract

Fertilin beta plays an important role in fertilization by its disintegrin domain as a sperm-specific antigen. This paper reviews its structure, localization and roles in fertilization, and suggests that fertilin beta, as an important target antigen, has a very promising value in the development of human immunocontraceptive vaccine.

Publication types

Review

MeSH terms

ADAM Proteins
Animals
Contraception, Immunologic
Fertilins
Fertilization
Humans
Male
Membrane Glycoproteins / chemistry
Membrane Glycoproteins / genetics
Membrane Glycoproteins / physiology*
Metalloendopeptidases / chemistry
Metalloendopeptidases / genetics
Metalloendopeptidases / physiology*
Vaccines / immunology

Substances

Membrane Glycoproteins
Vaccines
ADAM Proteins
ADAM2 protein, human
Fertilins
Metalloendopeptidases