Abstract
The number of patients with severe invasive group-G streptococcal (Streptococcus dysgalactiae subsp. equisimilis) infections has been increasing in Japan. The emm genotypes and SmaI-digested pulsed-field gel electrophoresis DNA profiles were variable among the strains isolated, suggesting there has not been clonal expansion of a specific subpopulation of strains. However, all strains carried scpA, ska, slo and sag genes, some of which may be involved in the pathogenesis of the disease.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adhesins, Bacterial*
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Aged
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Aged, 80 and over
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DNA Fingerprinting / methods
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DNA, Bacterial
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Electrophoresis, Gel, Pulsed-Field
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Endopeptidases / genetics
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Female
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Genetic Variation / genetics
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Genotype
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Humans
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Japan / epidemiology
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Male
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Middle Aged
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Molecular Epidemiology
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Polymerase Chain Reaction / methods
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Population Surveillance
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Seroepidemiologic Studies
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Serotyping
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Severity of Illness Index
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Streptococcal Infections / diagnosis
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Streptococcal Infections / epidemiology*
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Streptococcal Infections / microbiology*
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Streptococcus* / classification
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Streptococcus* / genetics
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Streptococcus* / pathogenicity
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Virulence / genetics
Substances
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Adhesins, Bacterial
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DNA, Bacterial
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Endopeptidases
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C5a peptidase