Tumor-induced rickets: usefulness of MR gradient echo recall imaging for tumor localization

J Pediatr. 2004 Mar;144(3):381-5. doi: 10.1016/j.jpeds.2003.11.023.

Abstract

An 11-year-old boy presented with a femur fracture, bone hypomineralization, and hypophosphatemia, suggesting tumor-induced rickets. Conventional radiologic techniques including magnetic resonance skeletal survey did not identify a tumor. Magnetic resonance gradient echo recall imaging demonstrated a 3-cm iliac tumor, the resection of which rapidly reversed metabolic abnormalities. This technique may be useful in identifying elusive tumors associated with tumor-induced rickets.

Publication types

  • Case Reports
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Bone Neoplasms / complications
  • Bone Neoplasms / diagnosis*
  • Bone Neoplasms / metabolism
  • Bone Neoplasms / surgery
  • Child
  • Fibroblast Growth Factor-23
  • Fibroblast Growth Factors / analysis*
  • Fibroblast Growth Factors / blood
  • Hemangiopericytoma / complications
  • Hemangiopericytoma / diagnosis*
  • Hemangiopericytoma / metabolism
  • Hemangiopericytoma / surgery
  • Humans
  • Ilium*
  • Magnetic Resonance Imaging / methods*
  • Male
  • Reverse Transcriptase Polymerase Chain Reaction
  • Rickets / etiology

Substances

  • Fibroblast Growth Factors
  • Fibroblast Growth Factor-23