OBJECTIVE:Based on our previous clinical report of Nd:YAG laser irradiation as the means for deeling with cavernous hemangioma in deep oral-maxillofacial regions, this article detailed futher clinical application of this laser, trying to set up a non-surgical method for treatment of ang ioma. The relationship of laser dosage and therapeutic effect and possible surrounding tissue thermal damages were investigated.METHODS:Clinical study was carried out on 31 cases of deep hemangiomas involving different areas. Nd:YAG laser irradiation was delivered after surgical elevation of the flaps. All cases surveyed a follow up of 1.5 to 3 years.RESULTS:Posttherapeutic clinical and imaging examinations were taken to compare the findings before and after treatment. There are 29 cases with complete regression (93.55%), 2 cases with partial regression (6.45%). No complication occurred.CONCLUSION:Nd:YAG laser irradiation after flap elevation has been confirmed to be a valuable means to treat deep hemangiomas. It has the advantages of target tissue selection and normal tissue preservation, simplified manipulation and less bleeding, fewer complications and hihger successful rate.