HIV-Tat down-regulates telomerase activity in the nucleus of human CD4+ T cells

Cell Death Differ. 2004 Jul;11(7):782-4. doi: 10.1038/sj.cdd.4401346.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antibodies, Monoclonal / metabolism
  • Blotting, Western
  • CD4-Positive T-Lymphocytes / metabolism*
  • Cell Nucleus / enzymology*
  • Cells, Cultured
  • Down-Regulation
  • Gene Expression Regulation, Viral
  • Gene Products, tat / genetics
  • Gene Products, tat / metabolism*
  • HIV Infections / genetics*
  • HIV-1*
  • Humans
  • Jurkat Cells
  • Lymphocyte Activation / drug effects
  • Mitogens / pharmacology
  • Phytohemagglutinins / pharmacology
  • Telomerase / metabolism*
  • Time Factors
  • tat Gene Products, Human Immunodeficiency Virus

Substances

  • Antibodies, Monoclonal
  • Gene Products, tat
  • Mitogens
  • Phytohemagglutinins
  • tat Gene Products, Human Immunodeficiency Virus
  • Telomerase