Initial low-density lipoprotein response to statin therapy predicts subsequent low-density lipoprotein response to the addition of ezetimibe

Paul E Ziajka; Mary Reis; Sandra Kreul; Helen King

doi:10.1016/j.amjcard.2003.11.060

Initial low-density lipoprotein response to statin therapy predicts subsequent low-density lipoprotein response to the addition of ezetimibe

Am J Cardiol. 2004 Mar 15;93(6):779-80. doi: 10.1016/j.amjcard.2003.11.060.

Authors

Paul E Ziajka¹, Mary Reis, Sandra Kreul, Helen King

Affiliation

¹ The Florida Lipid Institute, Orlando, Florida 32806, USA.

PMID: 15019893
DOI: 10.1016/j.amjcard.2003.11.060

Abstract

This small retrospective study confirms the hypothesis that patients who are hyporesponders to statin therapy are hyper-responders to ezetimibe therapy and may help identify a patient population in whom ezetimibe would be particularly effective in lowering low-density lipoprotein cholesterol.

Publication types

Evaluation Study

MeSH terms

Anticholesteremic Agents / administration & dosage
Anticholesteremic Agents / pharmacology
Anticholesteremic Agents / therapeutic use*
Azetidines / administration & dosage
Azetidines / pharmacology
Azetidines / therapeutic use*
Cholesterol, LDL / blood*
Ezetimibe
Humans
Hyperlipidemias / blood
Hyperlipidemias / drug therapy*
Hyperlipidemias / pathology
Medical Records
Regression Analysis
Retrospective Studies
Treatment Outcome

Substances

Anticholesteremic Agents
Azetidines
Cholesterol, LDL
Ezetimibe