Abstract
The major constituents of fruits of Maclura pomifera are the prenylated isoflavones, osajin (1) and pomiferin (2). Since significant biological activities of extracts from the wood of M. pomifera were previously reported, the peroxynitrite scavenging activity, inhibition of lipid peroxidation, scavenging of DPPH and EROD activity of these two major substances were studied.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Benzopyrans / administration & dosage
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Benzopyrans / pharmacology*
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Benzopyrans / therapeutic use
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Biphenyl Compounds
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Cytochrome P-450 CYP1A1 / chemistry
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Free Radical Scavengers / administration & dosage
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Free Radical Scavengers / pharmacology*
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Free Radical Scavengers / therapeutic use
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Fruit
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Humans
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Isoflavones / administration & dosage
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Isoflavones / pharmacology*
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Isoflavones / therapeutic use
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Lipid Peroxidation / drug effects
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Maclura*
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Peroxynitrous Acid / chemistry
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Phytotherapy*
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Picrates / chemistry
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Plant Extracts / administration & dosage
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Plant Extracts / pharmacology
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Plant Extracts / therapeutic use
Substances
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Benzopyrans
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Biphenyl Compounds
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Free Radical Scavengers
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Isoflavones
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Picrates
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Plant Extracts
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Peroxynitrous Acid
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pomiferin
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osajin
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1,1-diphenyl-2-picrylhydrazyl
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Cytochrome P-450 CYP1A1