Using 18-fluoro-2-deoxyglucose positron emission tomography in detecting infectious endocarditis/endoarteritis: a preliminary report

Acad Radiol. 2004 Mar;11(3):316-21. doi: 10.1016/s1076-6332(03)00715-3.

Abstract

Rationale and objectives: We evaluated the effectiveness of positron emission tomography (PET) with 18-fluoro-2-deoxyglucose (FDG) in the detection of infectious endocarditis/endoarteritis.

Materials and methods: For this study, we recruited 6 patients (4 women, 2 men; age range, 35 - 78 years; mean age, 55.8 +/- 16.8 years) who were clinically diagnosed as having infective endocarditis/endoarteritis by their echocardiographic findings and by Duke criteria.

Results: For all 6 patients, we also found increased FDG uptakes in the corresponding areas detected in echocardiography.

Conclusion: FDG-PET appears to be a promising tool in diagnosing infective endocarditis/endoarteritis, and further prospective studies on a large scale to fully exploit the usefulness of FDG-PET for infective endocarditis/endoarteritis are needed.

Publication types

  • Evaluation Study

MeSH terms

  • Adult
  • Aged
  • Aortic Valve Stenosis / diagnostic imaging*
  • Arteritis / diagnostic imaging*
  • Arteritis / microbiology
  • Echocardiography
  • Endocarditis, Bacterial / diagnostic imaging*
  • Endocarditis, Bacterial / microbiology
  • Female
  • Fluorodeoxyglucose F18*
  • Heart Ventricles / diagnostic imaging
  • Humans
  • Lung / diagnostic imaging
  • Male
  • Middle Aged
  • Myocardium / metabolism
  • Pilot Projects
  • Positron-Emission Tomography* / methods
  • Radiopharmaceuticals
  • Staphylococcal Infections / diagnostic imaging*

Substances

  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18