ConSSeq: a web-based application for analysis of amino acid conservation based on HSSP database and within context of structure

Bioinformatics. 2004 Aug 12;20(12):1983-5. doi: 10.1093/bioinformatics/bth185. Epub 2004 Mar 25.

Abstract

Summary: A web-based application to analyze protein amino acids conservation-Consensus Sequence (ConSSeq) is presented. ConSSeq graphically represents information about amino acid conservation based on sequence alignments reported in homology-derived structures of proteins. Beyond the relative entropy for each position in the alignment, ConSSeq also presents the consensus sequence and information about the amino acids, which are predominant at each position of the alignment. ConSSeq is part of the STING Millennium Suite and is implemented as a Java Applet.

Availability: http://sms.cbi.cnptia.embrapa.br/SMS/STINGm/consseq/, http://trantor.bioc.columbia.edu/SMS/STINGm/consseq/, http://mirrors.rcsb.org//SMS/STINGm/consseq/, http://www.es.embnet.org/SMS/STINGm/consseq/ and http://www.ar.embnet.org/SMS/STINGm/consseq/

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acids / chemistry
  • Conserved Sequence
  • Databases, Protein*
  • Internet*
  • Protein Conformation
  • Proteins / analysis
  • Proteins / chemistry*
  • Proteins / classification
  • Sequence Alignment / methods
  • Sequence Analysis, Protein / methods*
  • Sequence Homology, Amino Acid*
  • Software*
  • Structure-Activity Relationship
  • User-Computer Interface*

Substances

  • Amino Acids
  • Proteins