Increasing prevalence of methicillin-resistant Staphylococcus aureus causing nosocomial infections at a university hospital in Taiwan from 1986 to 2001

Po-Ren Hsueh; Lee-Jene Teng; Wen-Hwei Chen; Huei-Ju Pan; Mei-Lin Chen; Shan-Chwen Chang; Kwen-Tay Luh; Fang-Yue Lin

doi:10.1128/AAC.48.4.1361-1364.2004

Increasing prevalence of methicillin-resistant Staphylococcus aureus causing nosocomial infections at a university hospital in Taiwan from 1986 to 2001

Antimicrob Agents Chemother. 2004 Apr;48(4):1361-4. doi: 10.1128/AAC.48.4.1361-1364.2004.

Authors

Po-Ren Hsueh¹, Lee-Jene Teng, Wen-Hwei Chen, Huei-Ju Pan, Mei-Lin Chen, Shan-Chwen Chang, Kwen-Tay Luh, Fang-Yue Lin

Affiliation

¹ Department of Laboratory Medicine and Committee of Infection Control, National Taiwan University Hospital, Taipei, Taiwan. [email protected]

Abstract

A rapid emergence of nosocomial methicillin-resistant Staphylococcus aureus (MRSA) infection (from 26.3% in 1986 to 77% in 2001) was found. The susceptibility of 200 nonduplicate blood isolates of MRSA and 100 MRSA isolates causing refractory bacteremia to 22 antimicrobial agents disclosed that glycopeptides, quinupristin-dalfopristin, and linezolid remained the most active agents.

MeSH terms

Anti-Bacterial Agents / pharmacology
Anti-Infective Agents / pharmacology
Ciprofloxacin / pharmacology
Cross Infection / epidemiology*
Cross Infection / microbiology*
Drug Resistance, Bacterial
Hospitals, University
Humans
Methicillin Resistance*
Microbial Sensitivity Tests
Staphylococcal Infections / epidemiology*
Staphylococcal Infections / microbiology*
Staphylococcus aureus / drug effects*
Taiwan / epidemiology

Substances

Anti-Bacterial Agents
Anti-Infective Agents
Ciprofloxacin