Ventricular assistance to bridge to transplantation

Surg Clin North Am. 2004 Feb;84(1):75-89, viii-ix. doi: 10.1016/S0039-6109(03)00221-4.

Abstract

In 2001, 2202 heart transplants were performed in the United States, leaving 4137 patients waiting who suffer from 30% annual mortality. Status I, Class IV heart failure patients have a 66% 1-year mortality rate and a survival approximating our worst cancers. Left ventricular assist devices (LVADs) first successfully bridged a patient to transplantation in 1978. LVADs have since functioned primarily thus, minimizing end-organ damage and providing rehabilitation potential for individuals awaiting transplantation. In this role, their effectiveness is well-established: they gain time for patients awaiting donors, preserve end-organ function, and provide potential for a high quality of life in and out of the hospital. This success has been the result of numerous advances in VAD technology, which this article discusses.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Equipment Design
  • Equipment Safety
  • Female
  • Heart Failure / diagnosis
  • Heart Failure / therapy*
  • Heart Transplantation
  • Heart-Assist Devices*
  • Humans
  • Male
  • Patient Selection
  • Risk Assessment
  • Sensitivity and Specificity
  • Ventricular Dysfunction, Left / diagnosis
  • Ventricular Dysfunction, Left / therapy*
  • Waiting Lists