Management of hardware infections following deep brain stimulation

Acta Neurochir (Wien). 2004 Apr;146(4):355-61; discussion 361. doi: 10.1007/s00701-004-0219-2. Epub 2004 Feb 13.

Abstract

Objective: To report our experience on hardware-related infections following deep brain stimulation (DBS).

Methods: The present article presents the retrospective clinical notes review of gained in a two-centre, single-surgeon study experience of 108 consecutive DBS cases between 1996 and 2002. In all patients the minimum follow-up was six months. One hundred and eight patients received an intracerebral electrode implantation and 106 underwent internalization.

Results: In total 178 electrodes were implanted with a mean follow-up of 42.6 months and a cumulative follow-up of 367.7 patient-years. Four patients (3.8%) developed an infection related to the DBS-hardware and all were initially treated with antibiotics. Two patients eventually required additional surgical treatment.

Conclusion: Infections due to DBS-hardware can result in considerable levels of morbidity. In certain cases antibiotic therapy may be adequate. In others, surgical intervention to externalise the electrodes may be necessary. In our experience, there was never a need to remove the electrodes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Anti-Bacterial Agents / therapeutic use
  • Brain Diseases / drug therapy*
  • Brain Diseases / etiology*
  • Brain Diseases / surgery
  • Electric Stimulation Therapy / adverse effects*
  • Electrodes
  • Female
  • Humans
  • Infections / drug therapy*
  • Infections / etiology*
  • Infections / surgery
  • Male
  • Middle Aged
  • Retrospective Studies

Substances

  • Anti-Bacterial Agents