Pulmonary hypoplasia and persistent pulmonary hypertension in the newborn with homozygous alpha-thalassemia: a case report and review of the literature

M J Bizzarro; J A Copel; H A Pearson; B Pober; V Bhandari

doi:10.1080/14767050412331312280

Pulmonary hypoplasia and persistent pulmonary hypertension in the newborn with homozygous alpha-thalassemia: a case report and review of the literature

J Matern Fetal Neonatal Med. 2003 Dec;14(6):411-6. doi: 10.1080/14767050412331312280.

Authors

M J Bizzarro¹, J A Copel, H A Pearson, B Pober, V Bhandari

Affiliation

¹ Department of Pediatrics, Yale-New Haven Hospital, New Haven, Connecticut, USA.

PMID: 15061322
DOI: 10.1080/14767050412331312280

Abstract

The survival of infants with homozygous alpha-thalassemia, once considered a lethal diagnosis, is now possible through in utero and postnatal diagnostic and therapeutic interventions. We report the survival of a newborn with homozygous alpha-thalassemia complicated by pulmonary hypoplasia and persistent pulmonary hypertension, an association not previously reported.

Publication types

Case Reports
Review

MeSH terms

Diagnosis, Differential
Erythrocyte Transfusion
Humans
Infant, Newborn
Male
Persistent Fetal Circulation Syndrome / complications
Persistent Fetal Circulation Syndrome / diagnosis*
Persistent Fetal Circulation Syndrome / therapy
Respiration, Artificial
alpha-Thalassemia / complications
alpha-Thalassemia / diagnosis*
alpha-Thalassemia / therapy