Status and management of blood lipids in Greek adults and their relation to socio-demographic, lifestyle and dietary factors: the ATTICA Study. Blood lipids distribution in Greece

Atherosclerosis. 2004 Apr;173(2):353-61. doi: 10.1016/j.atherosclerosis.2003.12.031.

Abstract

Objective: In this work, we assessed the status and management of blood lipids in a sample of cardiovascular disease free adult men and women from Greece. We also evaluated the effect of several socio-demographic, dietary and lifestyle habits on lipid levels.

Methods: The ATTICA Study is a population-based cohort that has randomly enrolled 1128 men and 1154 women (aged >18 years old), stratified by age-gender, from the greater area of Athens, during 2001-2002. Adherence to Mediterranean diet was assessed through a diet score that was based on a validated food-frequency questionnaire.

Results: Forty-six percent of men and 40% of women had total serum cholesterol levels >200mg/dl. Of them, 40% of men and 30% of women were unaware of their condition. Twenty-one percent of men and 7% of women had HDL-cholesterol levels <35 mg/dl. Twenty-eight percent of men and 13% of women had triglyceride levels >150 mg/dl. Fifteen percent of men and 12% of women had LDL-cholesterol levels >160 mg/dl and 52% of men and 48% of women had LDL >130 mg/dl. Of those who had known blood lipid abnormalities, 36% of men and 33% of women followed a dietary medication, 31% of men and 20% of women were receiving a pharmaceutical treatment (mainly statin) and the rest were untreated. Participants who adopted the Mediterranean diet and received statin, had on average 9% lower total cholesterol (P = 0.04), 19% lower LDL-cholesterol levels (P = 0.02) and 32% lower oxidized LDL-cholesterol levels (P < 0.001) compared to those who were untreated and adopted a Westernized diet.

Conclusions: We could speculate that about 3 million Greek adults had high total cholesterol levels. Adverse findings were also observed regarding the other investigated blood lipids. Mediterranean diet could be a complimentary mean to pharmaceutical treatment in reducing blood lipids.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Age Distribution
  • Aged
  • Chi-Square Distribution
  • Cholesterol, HDL / blood
  • Cholesterol, LDL / blood
  • Cohort Studies
  • Coronary Artery Disease / epidemiology
  • Coronary Artery Disease / prevention & control*
  • Coronary Artery Disease / therapy
  • Diet, Mediterranean*
  • Female
  • Greece / epidemiology
  • Health Surveys
  • Humans
  • Hyperlipidemias / diagnosis
  • Hyperlipidemias / epidemiology
  • Hyperlipidemias / therapy*
  • Hypolipidemic Agents / therapeutic use*
  • Life Style*
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Probability
  • Risk Assessment
  • Severity of Illness Index
  • Sex Distribution
  • Socioeconomic Factors

Substances

  • Cholesterol, HDL
  • Cholesterol, LDL
  • Hypolipidemic Agents