Severe fetal cytomegalovirus infection associated with cerebellar hemorrhage

J U Ortiz; E Ostermayer; T Fischer; B Kuschel; M Rudelius; K T M Schneider

doi:10.1002/uog.1021

Severe fetal cytomegalovirus infection associated with cerebellar hemorrhage

Ultrasound Obstet Gynecol. 2004 Apr;23(4):402-6. doi: 10.1002/uog.1021.

Authors

J U Ortiz¹, E Ostermayer, T Fischer, B Kuschel, M Rudelius, K T M Schneider

Affiliation

¹ Section of Perinatal Medicine, Department of Obstetrics and Gynecology, Technical University, Munich, Germany.

PMID: 15065194
DOI: 10.1002/uog.1021

Abstract

Cytomegalovirus (CMV) is the most common cause of congenital infection worldwide. We report on a fatal fetal manifestation of primary maternal CMV infection including cerebellar hemorrhage and hydrops. The diagnosis was established by maternal serological tests, culture and polymerase chain reaction testing of amniotic fluid and fetal blood. The pregnancy was terminated. Postmortem examination confirmed the diagnosis.

Publication types

Case Reports

MeSH terms

Abortion, Incomplete
Adult
Cerebellar Diseases / diagnosis
Cerebellar Diseases / diagnostic imaging
Cerebellar Diseases / virology*
Cerebral Hemorrhage / diagnosis
Cerebral Hemorrhage / diagnostic imaging
Cerebral Hemorrhage / virology*
Cytomegalovirus Infections / diagnosis*
Cytomegalovirus Infections / diagnostic imaging
Fatal Outcome
Female
Fetal Diseases / diagnostic imaging
Fetal Diseases / virology*
Humans
Pregnancy
Pregnancy Complications, Infectious* / diagnosis
Ultrasonography, Prenatal / methods