CDG IIx with unusual phenotype

J Inherit Metab Dis. 2004;27(1):103-4. doi: 10.1023/b:boli.0000016679.20481.4a.

Abstract

Congenital disorders of glycosylation (CDG) are a group of genetic diseases characterized by defective protein glycosylation. N-glycosylation defects are divided into two groups (I and II). CDG group II (types IIa to IIe) refers to defects in the Golgi processing of protein-bound glycans. We report a patient with CDG IIx and an unusual phenotype.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anemia, Hemolytic / etiology*
  • Carbohydrate Metabolism, Inborn Errors / complications
  • Carbohydrate Metabolism, Inborn Errors / genetics*
  • Carbohydrate Metabolism, Inborn Errors / metabolism
  • Carbohydrate Metabolism, Inborn Errors / psychology
  • Chronic Disease
  • Creatine Kinase / blood*
  • Face / abnormalities*
  • Glycosylation
  • Humans
  • Infant
  • Male
  • Phenotype
  • Proteinuria / etiology*
  • Psychomotor Performance*

Substances

  • Creatine Kinase