Diprosopus associated with neural tube defect and facial cleft in the first trimester

Fetal Diagn Ther. 2004 May-Jun;19(3):246-50. doi: 10.1159/000076706.

Abstract

We report a case of diprosopus presenting with increased nuchal translucency of 5.3 mm at 14 weeks of gestation. Ultrasonographically, the fetus presented with micrognathia, anterior indentation of the cephalic pole, abnormal cerebral hemispheres with a cystic 4th ventricle and angulation of the spine. The fetal karyotype was normal (46,XX). Following termination of pregnancy, postmortem examination established the diagnosis of diprosopus tetraophthalmus with facial cleft of the 2 faces.

Publication types

  • Case Reports

MeSH terms

  • Abortion, Induced
  • Adult
  • Face / embryology*
  • Female
  • Fetus / abnormalities*
  • Fetus / pathology
  • Humans
  • Karyotyping
  • Neck / diagnostic imaging*
  • Neck / embryology*
  • Pregnancy
  • Pregnancy Trimester, Second
  • Spine / diagnostic imaging
  • Spine / embryology
  • Twins, Conjoined*
  • Ultrasonography, Prenatal*