A sulfido-bridged diiron(II) compound and its reactions with nitrogenase-relevant substrates

J Am Chem Soc. 2004 Apr 14;126(14):4522-3. doi: 10.1021/ja049417l.

Abstract

The active site iron-molybdenum cofactor of nitrogenase has sulfide-bridged pairs of redox-active, trigonal pyramidal iron atoms that are postulated to be the site of N2 transformation. A synthetic compound is described in which two three-coordinate iron(II) ions are bridged similarly by sulfide. The compound binds nitrogen donors to become trigonal pyramidal and cleaves the N-N bond of phenylhydrazine with oxidation of iron(II) to iron(III).

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Ferrous Compounds / chemical synthesis
  • Ferrous Compounds / chemistry*
  • Molybdoferredoxin / chemistry*
  • Nitrogenase / chemistry*
  • Nitrogenase / metabolism
  • Substrate Specificity
  • Sulfides / chemical synthesis
  • Sulfides / chemistry*

Substances

  • Ferrous Compounds
  • Molybdoferredoxin
  • Sulfides
  • Nitrogenase