Abstract
An anonymous 14.9-kb rrn-containing HindIII fragment is strongly linked to Escherichia coli strains causing neonatal meningitis. We show in this report that this fragment does not encode new virulence factors but lacks arpA, a gene common in avirulent E. coli strains, and we developed a PCR test to detect this fragment.
MeSH terms
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Deoxyribonuclease HindIII / metabolism*
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Escherichia coli / classification*
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Escherichia coli / genetics*
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Escherichia coli / isolation & purification
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Escherichia coli Infections / microbiology
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Escherichia coli Proteins / genetics
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Gene Deletion
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Genetic Markers
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Humans
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Infant, Newborn
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Meningitis, Escherichia coli / microbiology*
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Polymerase Chain Reaction
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rRNA Operon / genetics*
Substances
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Escherichia coli Proteins
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Genetic Markers
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Deoxyribonuclease HindIII