Copper-catalyzed synthesis of 1,3-enynes

Craig G Bates; Pranorm Saejueng; D Venkataraman

doi:10.1021/ol049706e

Copper-catalyzed synthesis of 1,3-enynes

Org Lett. 2004 Apr 29;6(9):1441-4. doi: 10.1021/ol049706e.

Authors

Craig G Bates¹, Pranorm Saejueng, D Venkataraman

Affiliation

¹ Department of Chemistry, University of Massachusetts-Amherst, 710 North Pleasant Street, Amherst, Massachusetts 01003, USA.

PMID: 15101762
DOI: 10.1021/ol049706e

Abstract

[reaction: see text] We report a copper(I)-catalyzed procedure for the synthesis of 1,3-enynes. This method affords a variety of enynes in good to excellent yields. This method can tolerate a variety of functional groups, does not require the use of expensive additives, and is palladium-free.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Alkynes / chemical synthesis*
Alkynes / chemistry
Catalysis
Copper / chemistry*
Molecular Structure

Substances

Alkynes
Copper