Convenient and efficient reduction of 1,1'-binaphthyls to H8-1,1'-binaphthyl derivatives with Pd and Ru catalysts on solid support

Andrei Korostylev; Vitali I Tararov; Christine Fischer; Axel Monsees; Armin Börner

doi:10.1021/jo0497609

Convenient and efficient reduction of 1,1'-binaphthyls to H8-1,1'-binaphthyl derivatives with Pd and Ru catalysts on solid support

J Org Chem. 2004 Apr 30;69(9):3220-1. doi: 10.1021/jo0497609.

Authors

Andrei Korostylev¹, Vitali I Tararov, Christine Fischer, Axel Monsees, Armin Börner

Affiliation

¹ Leibniz-Institut für Organische Katalyse an der Universität Rostock e.V., Buchbinderstrasse 5-6, 18055 Rostock, Germany.

PMID: 15104470
DOI: 10.1021/jo0497609

Abstract

Hydrogenation of chiral 2,2'-functionalized 1,1'-binaphthyls with Pd and Ru solid-supported metal catalysts was found to be a clean and convenient pathway to 5,5',6,6',7,7',8,8'-octahydro-1,1'-dinaphthyl derivatives. In most cases no racemization was observed in the course of the reaction.