Prediction of cerebral ischemic tolerance during carotid cross-clamping by angiographic criteria

Eur J Vasc Endovasc Surg. 2004 Jun;27(6):640-5. doi: 10.1016/j.ejvs.2004.02.005.

Abstract

Objective: To evaluate the prognostic value of angiographic criteria and internal carotid artery (ICA) stump pressure for shunt placement in carotid surgery under local anaesthesia.

Design: Prospective clinical trial at a university hospital.

Materials and methods: In 120 patients a cerebral angiography was initiated before undergoing carotid surgery. Seventy-five percent of the patients were neurologically asymptomatic, 13% had transient ischaemic attacks and 12% suffered from previous strokes. The operation was exclusively performed under local anaesthesia and prior to cross-clamping the ICA stump-pressure was measured. A shunt was inserted only if hemispheric symptoms or unconsciousness occurred independent of the angiographic findings or stump pressure.

Results: In 23% (27/120) a shunt became necessary and significantly (p<0.001) more often when there was a cross-flow towards the contralateral hemisphere (12/20=60%) or if the contralateral ICA was occluded (9/13=69%). The sensitivity for not needing a shunt in case of cross-flow towards the side of operation was 91% (52/57) whereas the specificity was 35% (22/63). ICA stump-pressure was significantly reduced in patients requiring a shunt (31 mmHg) compared to those not needing a shunt (53 mmHg) (p<0.001), but no definitive threshold value was found determining the need for shunting. Intraoperatively, no persistent neurological complication developed.

Conclusions: Angiographic cross-flow was a good, but not perfect predictor for the need of an intraoperative shunt.

MeSH terms

  • Aged
  • Anesthesia, Local
  • Arteriovenous Shunt, Surgical
  • Blood Pressure
  • Brain Ischemia / diagnostic imaging
  • Brain Ischemia / etiology*
  • Carotid Artery, Internal / physiopathology
  • Cerebral Angiography*
  • Cerebrovascular Circulation / physiology
  • Endarterectomy, Carotid*
  • Female
  • Humans
  • Intraoperative Care
  • Ischemic Attack, Transient / etiology
  • Male
  • Multivariate Analysis
  • Prospective Studies
  • Stroke / etiology