Emission of 694-nm laser energy from a Q-switched ruby laser causes photodestruction of cutaneous pigment. The 40-nanosecond pulse duration of Q-switched ruby laser light initiates specific damage to melanosomes thus allowing selective treatment of benign pigmented lesions. Nevus of Ota is a benign facial oculocutaneous melanosis that has melanosomes lying deeply within the dermis. We report the successful use of the Q-switched ruby laser in the treatment of two patients with the nevus of Ota.