A pediatric cluster of Shigella dysenteriae serotype 1 diarrhea with hemolytic uremic syndrome in 2 families from France

Clin Infect Dis. 2004 May 1;38(9):e96-9. doi: 10.1086/383474. Epub 2004 Apr 15.

Abstract

We report a cluster of pediatric diarrhea due to Shigella dysenteriae serotype 1 involving 11 children in France, including the index case, who had returned from Senegal. Child-to-child transmission was documented by ribotyping. Five children developed hemolytic uremic syndrome (HUS). On the basis of our findings, the choice of antimicrobial treatment for infections with S. dysenteriae serotype 1 should take into account widespread drug resistance and the risk of HUS.

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Child
  • Child, Preschool
  • Diarrhea / complications
  • Drug Resistance, Bacterial
  • Dysentery, Bacillary / complications*
  • Female
  • France
  • Hemolytic-Uremic Syndrome / epidemiology
  • Hemolytic-Uremic Syndrome / etiology*
  • Humans
  • Infant
  • Male
  • Risk Factors
  • Shigella dysenteriae* / drug effects

Substances

  • Anti-Bacterial Agents