Cyclin C makes an entry into the cell cycle

Dev Cell. 2004 May;6(5):607-8. doi: 10.1016/s1534-5807(04)00137-6.

Abstract

From yeast to humans, cell cycle progression is orchestrated by the oscillation of kinase activities associated with cyclins. In an article published recently in Cell, Ren and Rollins investigate mechanisms controlling the G0/G1 transition in quiescent cells and identify new cyclin C/Cdk3 complexes as key regulators of cell cycle reentry in human cells.

Publication types

  • Review

MeSH terms

  • Animals
  • Cell Cycle / genetics*
  • Cyclin C
  • Cyclin-Dependent Kinase 3
  • Cyclin-Dependent Kinases / metabolism*
  • Cyclins / metabolism*
  • G1 Phase / genetics
  • Humans
  • Resting Phase, Cell Cycle / genetics
  • Retinoblastoma Protein / metabolism

Substances

  • CCNC protein, human
  • Cyclin C
  • Cyclins
  • Retinoblastoma Protein
  • CDK3 protein, human
  • Cyclin-Dependent Kinase 3
  • Cyclin-Dependent Kinases